Reply To: Oral and Whole Body Health

#3457 Score: 0
shirdent
Member

    Here’s the thing, until we can decide on a way to diagnose periodontal disease all these studies will give questionable results. How was PD determined? Bone loss? That can come from a number of problems, only one of which is perio related.

    Pathogens? they must live in a caustic biofilm in order to be damaging.

    Xrays? You’re kidding, right?

    Bleeding on probing? how are the probers calibrated? What pressure was used on the probe?
    Was the patient already pregnant? that causes tissue changes that mimic perio

    Is it ok for a pregnant woman to have an infected open wound anywhere? NO!

    Does it cause preterm birth? who cares? Clean it up!

    Was Semmelweis wrong, he sure was for a long time. Now look! You can’t go anywhere without seeing hand sanitizers everywhere! It’s hard being so far forward!:rolleyes:

    The science of biofilm shows us that the body reacts to the presence of the film by increasing inflammatory cascades and the chemistry that comes with fighting infection. That’s not good for anyone. It’s also hard to study, as the effects take a long time to show.

    Shirley Gutkowski

    Arch Gynecol Obstet. 2010 Dec 1. [Epub ahead of print]
    Periodontal disease and perinatal outcomes.
    Matevosyan NR.

    Open Medical Institute, Salzburg, Austria

    PURPOSE: To elucidate plausible associations between periodontal disease (PD) and pregnancy events through meta-analysis of original research published between 1998 and 2010.

    METHODS: One hundred and twenty-five randomized, case-control, matched-cohort studies on pregnancy and postpartum specifics in women with PD are identified through PubMed, LILACS, and Cochrane Register. Meta-study is performed on a sample of 992 births allocated from studies of level I-II-1 evidence. An oral inflammation score (OIS) is composed from parameteric and observational components of maternal PD. Pearson arrival process is modeled for exchangeable correlations.

    RESULTS: Women with preeclampsia and preterm birth have poor periodontal parameters in both, treatment and placebo groups (OR 1.94-2.9). In puerperae with severe periodontitis birth weight is negatively correlated with maternal probing depth (r = -0.368), and C-reactive protein (r = -0.416). Higher rates of tobacco use (RR 3.02), bacterial vaginosis (RR 2.7), clinical attachment level (OR 2.76), and fetal tyrosine kinase (OR 1.6) contribute in increased rates of preeclamsia (RR 1.68), and prematurity (RR 2.75). After adding confounders into the model OIS remains significantly associated with preterm birth (OR 2.3).

    CONCLUSIONS: Maternal PD has strong associations with preeclampsia and prematurity.