Reply To: Oral and Whole Body Health

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January 9, 2011 at 3:55 am #3437 Score: 0
Harrison
Keymaster
    2 pts

    This article is interesting, as it confirms what other labs (with molecular diagnostics) are finding: that (not only bacteria) can be more virulent or pathogenic than others. This issue has been researched, documented and published myriad times in the past five or six years.
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    Virulence. 2010 Jul-Aug;1(4):254-9.
    Examination of maternal gingival crevicular fluid for the presence of selected periodontopathogens implicated in the pre-term delivery of low birthweight infants.
    Africa CW, Kayitenkore J, Bayingana C.

    Faculty of Science, Department of Medical Biosciences, University of the Western Cape, Belville, South Africa.

    BACKGROUND: Reports show that more than 20 million infants world-wide are born prematurely with 95% of all pre-term births occurring in developing countries. Oral colonization of gram-negative anaerobes has been implicated as a risk factor for preterm delivery of low birth weight infants.

    MATERIALS AND METHODS: This study comprised 200 women admitted to the department of obstetrics and gynecology of the teaching hospital of Butare in Rwanda. Gingival crevicular fluid was collected from each quadrant of the mother’s mouth (using paper points) within 24 hours of delivery. A dichotomous score of presence or absence of gingival inflammation was recorded for each patient along with demographic data such as age, marital status etc. Samples were examined by PCR for the presence of Aggregatibacter actinomycetemcomitans and selected members of the red and orange complexes described by Socransky et al., (1998), and their presence associated with age, gingival inflammation and pregnancy outcomes.

    RESULTS: Association of bacterial species with the risk of periodontal disease and thus the risk of preterm delivery was only observed when they occurred in pairs or groups of three or more. Aa appeared to be a necessary co-factor for significant associations of bacterial groups with the variables recorded.
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    And another:

    Minerva Stomatol. 2010 Oct;59(10):543-50.
    Effect of periodontal treatment on the incidence of preterm delivery: a systematic review.
    Pimentel Lopes De Oliveira GJ, Amaral Fontanari L, Chaves De Souza JA, Ribeiro Costa M, Cirelli JA.

    UNESP, Division of Periodontology, São Paulo State University, Department of Diagnosis and Surgery, School of Dentistry at Araraquara, Araraquara, SP, Brazil

    Preterm birth is a major problem in public health in developed and developing countries and the search for risk factors of this event is important. The aim of this study was to review the effect of periodontal treatment on the incidence of preterm delivery. A wide research was executed considering an evaluation period between November of 1998 and October of 2009 at MEDLINE/PUBMED databases.

    The selection strategy consisted of the search for the following key-words: “periodontal therapy” or “periodontal disease” and “pregnancy outcome” or “preterm birth”. The search was limited for articles written in English. The randomized clinical trials that evaluated the effect of the non-surgical periodontal treatment on the incidence of Preterm Low Birth Weight (PLBW) were selected.

    In a total of 7 papers selected, the incidence of PLBW was lower in groups of women who were submitted to periodontal treatment. Reductions of Preterm Birth (PTB) ranged from 0.8% to 28.01%, while reduction of Low Birth Weight (LBW) ranged from 0.44% to 33%. In studies that analyzed these two variables together, . The majority of the studies concluded that non-surgical periodontal treatment in pregnant women reduces incidence of preterm babies with low weight.