As the science and biology of Lyme disease continues to be ignored by many doctors and policymakers, progress continues. And so does the work of great people: thinkers and doers who genuinely care about helping people! I am honored to share a recent interview with Dr. Alan MacDonald, a gifted researcher, passionate educator and all-around good guy. His wealth of knowledge in the biology of Lyme disease will knock your socks off!

A few excerpts:

“…And I was able to grow the Lyme spirochete from four of four Alzheimer’s brains from George Glenner’s Alzheimer’s Brain Bank at the University of California at San Diego…”

“…the work continues and we are finishing a case study from a German physician who had Alzheimer’s disease; had high levels of antibodies to the Lyme spirochetes, actually three different strains in his spinal fluid…”

“…finding the spirochete at the site of the Alzheimer injury is not any different from finding the strep at the site of the strep throat, or finding the bacteria at the site of the ruptured appendix, or finding the syphilis spirochete at the site of the general paresis. There is no difference…”

“…Now think about it. One spirochete and one lineage, one set of proteins, one DNA, is going to be the ruler for diagnosing any and all of the bacterial spirochetal and Borrelia infections in the United States. We now know there are at least 100 different genotypes of Borrelia burgdorferi for our USA type…”

“…the syphilis spirochete could outwit the immune system in many, man ways. And it could do inside of cells and hide inside of cells. It could hide in areas of the body which we call sanctuary sites where the immune system does not get to very easily; like it hides in brain because brain is a sanctuary site. It hides in the eye because the eye is a protected site and the immune system does not get into the eye..”

“…The ultimate survival mechanism is the biofilm. And what is a biofilm? Biofilm is different from a single microbe. It is a community of microbes. And the community of microbes are specialized. So you have the equivalent of carpenters, electricians, accountants, you know, sanitary engineers. And all these specialized members of the community have specialized functions which are different from the single microbe, which started the community growing. And, they surround this community with a protective layer of what is called extracellular matrix. It is a protective layer of material that includes DNA from the bug, proteins that came from the bugs that are once living but are now dead, and they form a glue that holds the community together. The community is serviced by it’s own waste removal system. It has canals, water canals. So, nutrients can flow in and waste can flow out. It has its own communication system. It has both nano wires like electrical wires or telephone wires. It has nano tubes…”

  • Jackie de Vries

    I hope you might open up your research to look at chlorine dioxide treatment for these conditions – or at least let the community of sick people know it is a possibility for helping them recover!

  • Lymeinsideme

    I am very sick from lyme. I have been on antibiotics now for 8 months. I can feel it growing back and am very scared I’m going to loose my life. I am a mom of four trying to hang on. It is primarily in my nervous system and can feel it in my brain . I have tremors at night , can feel it in my feet and stomach. It defiantly talks and buzzes in sync . It’s scary as hell and the doctors won’t give me an iv? I don’t really understand why? I am not sure if I will survive this , I’m very strong person but very scarred . Every night I go to sleep it comes alive, I do ok durning the day but I feel like its waking up and spreading . Is anybody there to help ? I live on Long Island NY and most doctors are very ignorant to this cause. Is there any doctor who can help me? Can someone recommend a neurologist that specializes in lyme and can help me? I am seeing a lyme doctor but they are not aggressive enough ,…..I talk but nobody hears me

  • My son has had a severe case of neuro-lyme, with identical symptoms with tertiary syphilis and general paresis. It’s taken 5 yrs and $1,000,000 in healthcare expenses to heal his mengio-encephalitis. All due to the right combination of oral abx and doses. I believe, as Dr Jemsek does, that the tuberculosis model is the best trx model for chronic lyme. I love your new documentary. Continue your important extension of Joseph Bigger’s research. I’m somewhat dismayed at the recent blanket recommendation by ILADS for continuous abx dosage. PK/PD research with it’s inclusion of PAE and PALE effects on persisters appears crucial.
    Thank you.
    PS: Could the liposomal delivery system for abx and possible variable release times aid the timing of effective abx, reduce toxicity, target delivery, and increase lipid penetration?