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More on this subject. This is good news for those of you that consume foods and drinks rich on catechins. A few comments:
– red wine is rich in catechins, but some reds have more than others. Region and type decide this. White wines have less.
– many bacteria can form their own biofilms without help. This abstract hints that Eikenella corrodens has its own super-duper powers, but it’s not unique by any measure.
– many natural foods and substances are “quorum inhibitors.” Duh.
Biosci Biotechnol Biochem. 2010;74(12):2445-50. Epub 2010 Dec 7.
The inhibitory effects of catechins on biofilm formation by the periodontopathogenic bacterium, Eikenella corrodens.
Matsunaga T, Nakahara A, Minnatul KM, Noiri Y, Ebisu S, Kato A, Azakami H.
Department of Biological Chemistry, Faculty of Agriculture, Yamaguchi University, Yamaguchi, Japan.
Eikenella corrodens is a periodontopathogenic bacterium that forms biofilm even by itself. In this study, we investigated the inhibitory effects of catechins on E. corrodens biofilm formation. Biofilm formation was inhibited by the addition of 1 mM of the catechins with the pyrogallol-type B-ring and/or the galloyl group. The catechins with the galloyl group were effective at smaller doses than those with only the pyrogallol-type B-ring. An inhibitory effect was observed even when these catechins and gallic acid were added at sub-minimal inhibitory concentration (MIC) or at concentrations that showed no bactericidal effect.
These results suggest that some catechins at sub-MIC might inhibit biofilm formation. No inhibitory effect of catechins at sub-MIC on biofilm formation was observed in the luxS deletion mutant. Our studies suggest that some species of catechins with the galloyl group affect autoinducer 2-mediated quorum sensing and thereby inhibit biofilm formation by E. corrodens.